Last updated: July 2, 2025
The 2025 Guide to EBC-46 (Blushwood Berry Extract/Tigilanol Tiglate)
Everything you need to know about this powerful natural compound. We’ll explore the science, the benefits, and what you must look for in a high-quality supplement.
Words by
Michelle Nix
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Published on: July 2, 2025
If you're searching for EBC-46, you are likely on a journey to support your health in a powerful, natural way. You're in the right place. For centuries, the seeds of the Blushwood Berry were a closely-held secret of the Australian rainforest. Today, the potent compound found within those seeds—EBC-46—is at the forefront of natural wellness. This guide will give you the clear, data-backed information you need.
What is EBC-46? The Science, Simplified
The Science Behind the Seed
EBC-46, also known by its scientific name Tigilanol Tiglate, is a unique organic compound found exclusively in the seed of the Fontainea picrosperma (Blushwood) tree.
It is classified as a protein kinase C (PKC) activator. In simple terms, when introduced to the body, it stimulates a highly localized and specific response, marshaling the body’s own natural defense and repair mechanisms to the area. This unique function is what makes it a subject of intense scientific interest for a variety of health applications.
How EBC-46 Supports Your Health Goals
A Holistic Approach to Natural Wellness
Supporting Cellular Health EBC-46 helps support the body's natural processes for identifying and dealing with abnormal cells, promoting healthy cellular function and growth.
A Natural Inflammatory Response The compound encourages a healthy and natural inflammatory response, which can aid in soothing chronic discomfort and supporting joint health.
Skin Rejuvenation & Healing When applied topically or taken internally, EBC-46 supports the body's innate ability to repair and rejuvenate skin tissue, making it a powerful ally for various skin issues.
Overall Vitality & Defense By activating key cellular pathways, EBC-46 contributes to overall wellness, bolstering the body’s natural defenses and promoting a state of balance and vitality.
Buyer's Guide: The 5-point Quality Checklist
Not All EBC-46 Is Created Equal. Before You Buy, Demand This:
✅ Traceable Source & Purity: Is it sourced directly from pure Blushwood Berry seeds in a controlled, monitored environment?
✅ Third-Party Lab Testing: Does the company provide proof of independent lab testing for purity and potency?
✅ Brand Transparency & Guarantee: Does the company offer a satisfaction guarantee? Do they operate with full transparency?
✅ Verifiable Customer Reviews: Are there numerous, verifiable reviews from real customers sharing their success stories?
✅ Global & GMP-Certified Operations: Is the product manufactured in a GMP (Good Manufacturing Practice) certified facility and shipped reliably from secure, local warehouses?
Why Choose Blushwood Health?
Blushwood Health is the Clear, Trustworthy Choice.
At Blushwood Health, we don't just meet the standard for a premium EBC-46 supplement—we set it.
Our Source: We source our EBC-46 exclusively from Blushwood Berry seeds grown in a highly controlled, sustainable environment.
Our Promise: Every batch is third-party lab-tested for purity. We are proud to be GMP-certified.
Our Guarantee: We are so confident in our product that we offer a 60-Day Satisfaction Guarantee.
Our Proof: Trusted by over 50,000 customers worldwide with multiple 5-star reviews.
Authoritative Resources on EBC-46
Source 1: The First-in-Human Clinical Trial
Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46)
Source: The Lancet (via PubMed Central / National Library of Medicine)
Read the Study on PubMed
Source 2: The National Cancer Institute Listing
Clinical Trials Using Tigilanol Tiglate
Source: National Cancer Institute (NCI)
Source 3: The Mechanism of Action Study
Intra-Lesional Injection of the Novel PKC Activator EBC-46 Rapidly Ablates Tumors in Mouse Models
Source: PLOS ONE (via PubMed Central)
Source 4: The Official Developer Research Hub
Human Oncology - QBiotics
Source: QBiotics Group Limited
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Tincture 08
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PureSeed Capsules
For systemic, daily support of your body's natural defenses.
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Real Stories From Real Customers
"I used Blushwood to save my dog. He had two biopsies 18 months ago and was diagnosed with aggressive bone cancer and given 3 months to live. I fed him Blushwood (1/2 capsule of powder a day along with Kakadu plum, Wild Apricot and Boab powder sprinkled on his dinner). He was declared free of cancer after he had lived way beyond the 3 months (and they gave him another blood test that showed he was clear of cancer). He is a 6 year old maltese cross." - Mrs. Range
"I’ve been using the capsules and the powder for over a year now. I discovered the product while looking for natural and effective cancer fighters. I’m 54, and now I have abundant energy—running 6 miles 2–3 times a week. Almost 90% of my inflammation is gone (mind you, I push my body hard at work and in the gym regularly). The results come gradually, but at some point, you realize that you just feel better, and the symptoms and illnesses have subsided. I’ve been taking it daily for over a year now—4 to 6 capsules a day. I also use omega-3s, Pycnogenol, zinc, mushroom extracts, and many other supplements. Customer service is also great. I had an issue with a shipment, and they immediately replaced the products." - Mike Giapi
"I’ve been amazed by the tincture. When I applied a few drops to moles and tough skin buildup on my scalp, the spots—some of which were quite large—completely disappeared after a few weeks. It’s remarkable. I had tried another Blushwood tincture from Amazon before discovering this company, but this is the one that truly works. I keep touching the area that was treated, and the flaw is actually gone. My husband is taking the capsules for his prostate cancer, and he’s so inspired by my results that he’s expecting miraculous outcomes too. Thank you, thank you!" - Leah Matson
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Frequently Asked Questions
What exactly is Blushwood Berry extract?
The Blushwood Berry (Fontainea picrosperma) is a rare Australian rainforest fruit. Our products use a potent 10:1 concentrated extract from the plant's seed, which is where its unique and scientifically studied bioactive compound, EBC-46, is found.
What is the difference between the PureSeed Capsules and the Tincture 08?
Both formulas deliver the same potent EBC-46 extract, but in different forms. The PureSeed Capsules are designed for simple, precise oral dosing. The versatile Tincture 08 allows for both internal use of EBC-46 (sublingually) and direct topical application.
How does Blushwood Health compare to other brands?
Our approach is simple: we deliver a potent, 500 mg dose of 10:1 concentrated Blushwood Berry seed extract with no unnecessary fillers, sourced from plants cultivated in a controlled environment. This commitment to purity is validated by rigorous third-party testing from Eurofins. The ultimate proof is the trust from both medical doctors and naturopaths who use our products in their clinics, and the fact that over 90% of our users recommend our products.
What is the recommended dosage of EBC-46?
We offer two suggested daily regimens based on your wellness goals.
For General Wellness:
1500 mg of extract per day. This is one (1) capsule or 0.5 ml of tincture, taken three times a day.
For Targeted Support:
3000 mg of extract per day. This is two (2) capsules or 1.0 ml of tincture, taken three times a day.
Best Practices:
For optimal results, take each dose before a meal.
Space your three doses evenly throughout the day (e.g., morning, afternoon, and evening).
How do I take the products for internal use?
For best results and optimal absorption of the EBC-46, we recommend taking your dose three times per day (morning, afternoon, evening), preferably before a meal. If using the tincture, shake the bottle well and hold the liquid under your tongue for 60-90 seconds before swallowing.
How do I use the EBC-46 tincture topically?
For topical skin application, apply the desired amount of the tincture to cleansed, dry skin twice daily. Gently massage the solution until the EBC-46 formula is fully absorbed.
When can I expect to see results from EBC-46?
Individual results vary. Many users report an initial benefit, such as a heightened sense of energy, within the first few weeks. For more significant, targeted results, we recommend a dedicated regimen for at least 3-6 months to allow the EBC-46 compound time to work synergistically with your body.
What is EBC-46?
EBC-46 is the specific, scientifically studied bioactive compound found within the Blushwood Berry seed. It is the focus of dedicated global research and is the molecule responsible for the extract's unique and powerful properties.
Is there scientific evidence for EBC-46?
Yes, there is significant and growing scientific evidence. The most conclusive validation for EBC-46 (Tigilanol Tiglate) is its approval by the U.S. Food and Drug Administration (FDA) as the veterinary drug STELFONTA®. In published clinical studies, this drug demonstrated a high success rate in treating canine tumors.
Building on this foundation, the biotechnology company QBiotics is leading the clinical development of EBC-46 for human use. Human trials are underway, investigating the compound as a direct injection into various solid tumors, including melanoma and head and neck cancers. The results are incredibly promising, with studies showing that EBC-46 can lead to rapid tumor destruction by activating a powerful, localized immune response.
Beyond these targeted effects, scientific observation has also highlighted the compound's remarkable influence on wound healing and cellular regeneration. Research has documented that following the initial inflammatory response, EBC-46 promotes rapid and high-quality healing of the treatment site, showcasing its potential in tissue repair and broader skin health.
Sources:
QBiotics Group: "Wound Healing". This page on the developer's website details the mechanism by which EBC-46 promotes high-quality wound healing after its primary mode of action.
European Medicines Agency (EMA): "Stelfonta, INN-Tigilanol Tiglate: EPAR - Public Assessment Report". This official regulatory document provides an overview of the pivotal study results, including the percentage of tumors achieving complete response.
QBiotics Group: "Human Clinical Programs". This page outlines the specific types of solid tumors being investigated in ongoing human trials for EBC-46.
How is your product tested for quality?
Our commitment to quality is validated by globally recognized standards. In addition to being produced in a GMP-certified facility, every batch undergoes third-party testing by Eurofins to ensure the purity and safety of our EBC-46 extract.
Are there any known side effects from EBC-46?
Our EBC-46 extract is a natural product and is generally well-tolerated. As with any dietary supplement, we recommend consulting with your healthcare provider before beginning any new regimen, especially if you have a pre-existing medical condition or are taking other medications.
Can I give EBC-46 to my pets?
Yes, we are honored that many customers use our products to support the wellness journeys of their pets, often with incredible success. You can read about their powerful experiences on our dedicated Reviews Page.
We do however recommend consulting with a veterinarian before giving any new supplement to your pet.
Are your products vegan?
Yes. Both the PureSeed Capsules and the Tincture 08 are 100% vegan-friendly. The capsules are made from Hypromellose (plant-based cellulose), and the tincture contains only botanical compounds.
What happens if I stop taking EBC-46?
The benefits are tied to consistent use. If you stop taking the supplement, your body will no longer receive the support from the EBC-46 compound and will gradually return to its previous state. There are no withdrawal effects.
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